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human genome cgh microarray kit 4 × 44k  (Agilent technologies)


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    Agilent technologies human genome cgh microarray kit 4 × 44k
    Human Genome Cgh Microarray Kit 4 × 44k, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+genome+cgh+microarray+kit+4+%C3%97+44k/pmc04176193-151-7-15
    Average 90 stars, based on 1 article reviews
    human genome cgh microarray kit 4 × 44k - by Bioz Stars, 2026-09
    90/100 stars

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    Microarray:

    Article Title: Design and validation of a pericentromeric BAC clone set aimed at improving diagnosis and phenotype prediction of supernumerary marker chromosomes
    Article Snippet: .. Array CGH analysis was performed using the Human Genome CGH Microarray Kit 4 × 44K (Agilent Technologies, Palo Alto, CA), which consists of 42,494 60-mer oligonucleotide probes covering the entire genome with an average spatial resolution of ~43 kb. .. From both test and sex-matched reference (Promega, Southampton, UK) samples, 3 μg of genomic DNA, previously extracted from probands’ whole blood using the GenElute TM Blood Genomic DNA kit (Sigma-Aldrich), was processed according to the manufacturer’s protocol.



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    Expression of DUSP1 and DUSP6 in neurofibroma and MPNST. A, Gene expression <t>microarray</t> showing DUSP transcripts with increased expression in plexiform neurofibroma tumors and MPNST solid tumors versus normal human Schwann cells. The scale bar on right shows mean log2-transformed normalized fold change. B, Immunoblot shows elevated DUSP1, p-DUSP1 and DUSP6 protein in Dhh Cre; Nf1 fl/fl mouse neurofibroma versus normal age-matched wildtype sciatic nerve (WT nerve). C, Immunoblot shows elevated DUSP, p-DUSP1 and DUSP6 protein in NF1−/− iHSC and MPNST cell lines versus NF1 WT iHSC. β-actin was used as a loading control. D, Copy number alteration (CNA) data analysis of plexiform neurofibroma (pNF), NF1-associated MPNST and sporadic MPNST.
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    Expression of DUSP1 and DUSP6 in neurofibroma and MPNST. A, Gene expression <t>microarray</t> showing DUSP transcripts with increased expression in plexiform neurofibroma tumors and MPNST solid tumors versus normal human Schwann cells. The scale bar on right shows mean log2-transformed normalized fold change. B, Immunoblot shows elevated DUSP1, p-DUSP1 and DUSP6 protein in Dhh Cre; Nf1 fl/fl mouse neurofibroma versus normal age-matched wildtype sciatic nerve (WT nerve). C, Immunoblot shows elevated DUSP, p-DUSP1 and DUSP6 protein in NF1−/− iHSC and MPNST cell lines versus NF1 WT iHSC. β-actin was used as a loading control. D, Copy number alteration (CNA) data analysis of plexiform neurofibroma (pNF), NF1-associated MPNST and sporadic MPNST.
    Human Genome Cgh Microarray Kit 4×44k, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Expression of DUSP1 and DUSP6 in neurofibroma and MPNST. A, Gene expression microarray showing DUSP transcripts with increased expression in plexiform neurofibroma tumors and MPNST solid tumors versus normal human Schwann cells. The scale bar on right shows mean log2-transformed normalized fold change. B, Immunoblot shows elevated DUSP1, p-DUSP1 and DUSP6 protein in Dhh Cre; Nf1 fl/fl mouse neurofibroma versus normal age-matched wildtype sciatic nerve (WT nerve). C, Immunoblot shows elevated DUSP, p-DUSP1 and DUSP6 protein in NF1−/− iHSC and MPNST cell lines versus NF1 WT iHSC. β-actin was used as a loading control. D, Copy number alteration (CNA) data analysis of plexiform neurofibroma (pNF), NF1-associated MPNST and sporadic MPNST.

    Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

    Article Title: Targeted inhibition of the dual specificity phosphatases DUSP1 and DUSP6 suppress MPNST growth via JNK

    doi: 10.1158/1078-0432.CCR-18-3224

    Figure Lengend Snippet: Expression of DUSP1 and DUSP6 in neurofibroma and MPNST. A, Gene expression microarray showing DUSP transcripts with increased expression in plexiform neurofibroma tumors and MPNST solid tumors versus normal human Schwann cells. The scale bar on right shows mean log2-transformed normalized fold change. B, Immunoblot shows elevated DUSP1, p-DUSP1 and DUSP6 protein in Dhh Cre; Nf1 fl/fl mouse neurofibroma versus normal age-matched wildtype sciatic nerve (WT nerve). C, Immunoblot shows elevated DUSP, p-DUSP1 and DUSP6 protein in NF1−/− iHSC and MPNST cell lines versus NF1 WT iHSC. β-actin was used as a loading control. D, Copy number alteration (CNA) data analysis of plexiform neurofibroma (pNF), NF1-associated MPNST and sporadic MPNST.

    Article Snippet: CNA data on 51 primary MPNSTs (NF1-associated and sporadic) was from a published GSE3388 data set (Agilent Human Genome CGH Microarray kit (4×44K)) ( 25 ).

    Techniques: Expressing, Microarray, Transformation Assay, Western Blot